Gutpro: A Recommended Probiotic

Gutpro: A Recommended Probiotic

There are few probiotic supplements that I recommend for people to use to help fix their gut, and Gutpro is one that I recommend. For example, I am one of the few dissenting opinions when it comes to recommending HSO “probiotic” supplements. I do not recommend HSO “probiotic” supplements because of a lack of efficacy and safety studies. I stopped recommending many different Bifido and Lacto containing probiotic supplements because some contained strains which either produced too much D-lactate or too much histamine, both of which can cause a lot of people issues. Is every probiotic supplement perfect for everyone? Sadly, no. Some people can still have issues with GutPro, just like they can have issues with any probiotic supplement. For most people, though, Gutpro can be beneficial, and I recommend it.

Why I Recommend Gutpro

One of the main probiotic supplements I have had success recommending is Gutpro. The strains in Gutpro do not produce histamine and most of the strains in the probiotic do not produce large amounts of D-lactate. It is safe for most people that have those issues to take and gain the digestive benefits of taking a great probiotic supplement. Gutpro powder is free of common allergens including milk, casein, fish, shellfish, eggs, gluten, tree nuts, peanuts, corn, gluten, yeast, and soy. Gutpro also tests each batch of probiotics for potency, strain integrity, and contamination. Gutpro is also free of any prebiotics, which may cause negative digestive symptoms. Depending on the prebiotic, they may feed overgrowth worsening symptoms.

The probiotics in Gutpro are freeze dried and technically shelf stable when kept at room temperature, although Corganic states that the strains in Gutpro will start to lose potency at temperatures greater than 95F. They offer dry ice shipping and cold packs for an additional cost. I recommend that if you live in an area with temperatures above 70F to use the dry ice shipping service to maintain that your probiotic supplement remains cold throughout transportation for maximum potency. I would also store the Gutpro Powder in the refrigerator when you receive it. They also offer measuring spoons at an additional cost which I recommend to achieve proper doses. Finally, Gutpro is produced in the United States and is manufactured and shipped in a GMP-compliant facility with filtered air systems and temperature control to maintain the potency of their supplements.

Health Concerns that Gutpro May Improve

  • Allergies (may increase Th2 reactions and sensitization in some people)
  • Asthma (may increase Th2 reactions and wheezing in some people)
  • Bile reflux
  • Bile malabsorption
  • Bloating
  • C. difficile infection
  • Crohn’s disease
  • D-lactate acidosis / sensitivity (it may also worsen)
  • Eczema
  • GERD (heartburn)
  • Histamine intolerance
  • IBS
  • Lactose intolerance
  • Leaky gut
  • LERD
  • Liver disease
  • Nutrient breakdown and absorption
  • SIBO (may needed to be given as a probiotic enema if you have reduced MMC function)
  • Ulcerative colitis
  • Upper gut overgrowth (H. pylori)
  • While taking antibiotics or if you are hospitalized to help increase immunity
  • Yeast overgrowth in the gut

Breakdown of Individual Strains in Gutpro

Bifidobacteria bifidum – A strain of Bifidobacteria that is usually found in the colonic and vaginal flora of humans. The probiotic has been shown to help maintain healthy flora, bolster the immune system, and help digest carbohydrates. Recent studies have shown that bifidum may relieve allergies by decreasing Th2 immune reactions and may help suppress allergic reactions by restoring proper immune regulation. 1 2 3

Bifidobacteria breve – A strain of Bifidobacteria found in the colonic and vaginal flora of humans. Cases of people with IBS have been shown to have a shortage of this important probiotic. In breastfed infants, breve has been shown to make up a majority of their gut bacteria. Breve ferments oligosaccharides in the digestive tract and also helps produce L-lactate. 4 5 6

Bifidobacteria infantis – A strain of Bifidobacteria that is found in both infant and adult human colonic flora. Infantis helps produce acids that impede colonization of opportunistic bacteria by lowering colonic pH. Studies have shown it to be beneficial in eliminating symptoms associated with IBS. 7 8 9

Bifidobacteria longum– A strain of Bifidobacteria that is found as flora in the large intestine. Bifidobacteria longum is also known to be one of the first colonizing probiotics in newborns. Bifidobacteria longum is important to the metabolism, fermentation, and digestion of some carbohydrates in the intestinal tract including oligosaccharides. Bifidobacteria longum can break down and ferment amino acids. The probiotic can also break down bile salts and bile acids so that some can be deposited in the stool and others reabsorbed properly during enterohepatic circulation, improving liver function, fat digestibility, and detoxification.

Bifidobacteria longum has been shown in studies to help improve lactose intolerance, prevent diarrhea, alleviate some food allergies, and help fight colonization of opportunistic bacteria in the colon. Finally, Bifidobacteria longum have been shown in studies to be able to help scavenge free radicals in the intestines and help prevent colorectal cancer. 10 11 12 13 14 15

Lactobacillus gasseri – A strain of Lactobacilli that is found in the upper gut and vaginal flora. It seems to help with weight maintenance, maintaining a healthy microbiome and competes with H. pylori to reduce its colonization. 16 17

Lactobacillus plantarum – A strain of Lactobacilli that is found in the human small and large intestine. It is used in the production of sauerkraut, kimchi, pickles, and sourdough bread. Plantarum is an excellent probiotic which has shown to be useful in the elimination of the symptoms associated with IBS. It can reform the gastrointestinal mucus barrier and inhibits opportunistic bacteria by making bactericidal peptides. Lactobacillus plantarum also prevents allergies, especially to soybeans. Finally, Lactobacillus plantarum stimulates the immune system by producing the amino acid L-lysine in the intestine. 18 19

Lactobacillus salivarius – A strain of Lactobacilli that is typically found in the oral cavity and upper gut of humans. It can also be found in the human intestinal system. Salivarius keeps opportunistic bacteria in the oral cavity in check so that dental caries will not occur. 20

Gutpro Conclusion

I do recommend probiotic supplements for some people to improve their digestive health, although the jury is still out on their efficacy and if they implant. Studies of people taking probiotic supplements show that CFU (colony forming unit) amounts of probiotics cultured in their stool return to normal a few weeks after supplementation. These results show that taking probiotic supplements may not cause them to implant and helps increase overall amounts of probiotic bacteria in our microbiome. It is possible that the ingestion of probiotics may only modulate the immune system and in doing so may benefit people greatly depending on the strain. For others, however, it may cause different immune reactions worsening their symptoms. In people with severe Th1 / Th2 dominance, it is hard for me to recommend Gutpro or any probiotic supplement for that matter.

Also, individuals with severe D-lactate issues may not be able to tolerate Gutpro. Some of the strains in Gutpro do produce small amounts of D-lactate, but most produce L-lactate which may balance lactate concentrations in the digestive tract reducing issues. Some people with D-lactate issues can tolerate Gutpro, while others may not; it is worth a shot to see if it improves your digestive health.

I recommend trying Gutpro Infant if you are having severe digestive issues or severe D-lactate issues. It might be better tolerated with half of the probiotic being comprised of Bifidobacteria infantis (a well-tolerated strain), and the removal of L. plantarum which can produce some D-lactate during plateau phases of the growth cycle. 21

People with severe immunocompromisation should use any probiotic supplement including Gutpro with caution because it may cause sepsis. Even though Lactobacillus is considered a probiotic genus, infections of the probiotic have been noted. These “infections” may not occur from colonization, but rather from increased Th1 or Th2 reactions which worsen symptoms through increased cytokine production by the immune system. 22

Start with small doses when taking probiotic supplements at first to see how you react to them. Increase the dosage if need be and if you can tolerate it well to see if your digestive health further improves. The best time to take the probiotic supplement is in the morning upon waking on an empty stomach with a glass of filtered water. I suggest waiting at least one hour afterward to eat breakfast so that the probiotics will hopefully survive passage through the stomach without having to contend with a lowered stomach pH during eating for increased chances of survival.

Gutpro has been forthcoming in information about the integrity of the probiotic supplement, and I respect that. They test each batch for its integrity and provide means of keeping the probiotic supplement cold and fresh from the time of manufacturing to delivery. Even though I have minor caveats with Gutpro, my caveats could be applied to most if not all probiotic supplements. If you are going to take a probiotic supplement, then you need to take one that can be trusted and has the right strains needed to help your digestive health recover. That is why I recommend Gutpro and have recommended it to some clients that I have coached with great results.

Corganic Probiotic Supplement Recommendations

  2. Black, Jacquelyn. Microbiology: Principles and Explorations, Wiley, May 1, 2012.
  3. Perlmutter, David, Brain Maker, Little, Brown and Company, 2015.
  4. Black, Jacquelyn. Microbiology: Principles and Explorations, Wiley, May 1, 2012.
  5. Perlmutter, David, Brain Maker, Little, Brown and Company, 2015.
  7. Black, Jacquelyn. Microbiology: Principles and Explorations, Wiley, May 1, 2012.
  8. Perlmutter, David, Brain Maker, Little, Brown and Company, 2015.
  15. Perlmutter, David, Brain Maker, Little, Brown and Company, 2015.
  18. Perlmutter, David, Brain Maker, Little, Brown and Company, 2015.
  1. Hi John,
    Would you recommend Custom Probiotics, they have no FOS, dairy, wheat, gluten, sugar, soy etc. and have 60 billion CFU’s per capsule with the strains: L. Acidophilus, L. Rhamnosus, L. Plantarum, B. Lactis, B. Bifidum. I am torn between this product and GutPro Powder. Should a GOS prebiotic also be taken with the probiotics?

    • Yes, I recommend them as well, great probiotic. Yes, taking GOS would feed the probiotics helping to culture a probiotic microbiome.

  2. John, Gutpro does not contain the reuteri or johnsonii strains, which have some decent research behind them. When I asked Gutpro, they avoided the question as to why they don’t include them. (That strategy actually made me less confident in them, as it was what a PR/Marketer would do.)

    What do you think of those strains and why isn’t your top recommendation something with one or both of those?

  3. Hello John.
    I found thru GI effects testing that I have high overgrowth of the following commensalism bacteria:
    Bacteroides prevotella and vulgatus
    Faecalubacterium prausnitzii
    Veillonella spp
    Escherichia coli
    Oxalobacter formigenes.

    I’m low on bifidos and my lactobacillus tho moderate to n presence is too weak to grow in culture.

    My fecal secretory iga is high and my M butyrate is low.
    Multiple food intolerances prevent dietary change. The food intolerances perpetuate the overgrowth

    Would I possibly benefit from trying to crowd those out by supplementing with a strong bifido/lactobacillus probiotic?
    Renew life’s 150billion count doesn’t help one bit…
    I’m at wits end here… please help

    • Maybe, but for most probiotics would not implant. That being said Gutpro is at least alive when it reaches you to differing degrees compared to most other probiotics, so its chance of implanting is better. What if an untested organism is causing your issues? Ingestion of targeted prebiotics like collagen, Sunfiber, and GOS might help as well.

  4. Would love some info on adrenal support. I have submitted a saliva test to a lab and my adrenals are shot. I have take son Adapticrin I believe it’s called. What foods work also. Thank you

  5. Why does gut pro say to be taken with food when I have always been told to take probiotics on an empty stomach. How do I take the powder form? You say on an empty stomach, they say with food, not liquid. But how do I take it. Even the capsules say to be taken with food. I would prefer to take them on an empty stomach, which makes more sense, but the company doesn’t recommend it. Please help me clear up this confusion because my family is on stage 2 of the gaps diet and ran out of our other brand of probiotics so I purchased gut pro powder. It doesn’t seem to be working. Heartburn and constipation have returned in only 3 days of use.

    • It would appear that they say to take with food to prevent stomach upset. Overly cautious in my opinion.

  6. Thank you I’ve been doing some reading on here and a couple of the Adrenal Fatigue websites you shared in one of your articles and after reading these I was looking forward to trying probiotics again. I had occasionally tried whatever brand I saw at the supermarket and never really noticed any positive results. But then I saw your article on Megaspore and was alarmed when I realized there was much for me to understand about probiotics. After reading a couple more on your site I think I’m going to try the Gutpro powder! I will let you know how it goes! P.S. If anyone was interested in those other links they are here ( here ( and here (

  7. I’ve been trying to research what it means when a person has high SIgA. I see lots of info on LOW SIgA, but am wondering what it means if I have HIGH SIgA. Mine is 567 (normal is 20-160). I have no idea what to do about it.


  8. my teenage daughter has SIBO-C and is on a herbal protocal for a month of Berberine, Neem and Allimed and is taking Iberogast daily. After this protocal we were planning on going on a probiotic, is Gutpro a good one for her SIBO do you think? Thanks for your help

  9. Hi! How would you know if you react to probiotics or have any symptoms such as d-lactate or severe immunocomprimisation? Sorry I’m new to this and am a nursing mom with a baby who has eczema. I’m suspecting I have gut issues and have passed it, but I’m worried now in giving probiotics since you mention these other symptoms. Any advice?

    • If you eat yougurt and you get brain fog you have issues with D-lactate more than likely. I doubt you have severe immunocomprimisation unless you have autoimmune issues or cancer for example.

  10. Ergomax has gutpro in europe.

  11. How long would you suggest taking this probiotic if one is taking antibiotics for a UTI?

  12. Hi John, can you recommend me a similarly great probiotic that doesnt cause histamin issues and also dairy/gluten free but available in Europe? Id like to use it as part of my SIBO treatment. Also, are you available for counselling via email? I would need some guidance :)

    • Yes, send me an E-mail,

    • I am writing from the UK, with the same question: can you help me? I became excited by the information about Megaspores probiotics.
      A few years ago a nutritionist in London sent my poo sample to the USA for testing. It found that a key good bacterium was missing. Unfortunately I don’t remember which one.
      My IBS became acute and I started on the Fodmaps diet, which has been very helpful.
      The main programme here recommends a probiotic called Symprove. I’ve been taking it daily for at least a year, but I still have unwanted symptoms. It’s expensive, and I think it’s time to try something else.

    • I am unaware of any that are in Europe. Yes, I am contact me at

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